Using a clean stirring rod, place a crystal of salicylic acid into the first test tube. To each test tube add 1 drop of iron(III) chloride) solution.
SAFETY CONSIDERATIONS Wear goggles throughout this experiment.
This experiment uses salicylic acid, acetic anhydride and phosphoric acid.
After the reaction takes place, water is added to destroy the excess acetic anhydride and cause the product to crystallize.
The aspirin is then collected, purified by recrystallization, and its melting temperature measured.
If you spill some, wipe it up with a wet paper towel and throw the towel in the trash.
The acetic anhydride and sulfuric acid can cause bad burns.
If you spill a lot of either of these, notify your instructor.). Using the graduated cylinder located under the hood, measure out 7.00 m L of acetic anhydride and add this to the flask.
Transfer this to a 125 m L Erlenmeyer flask using a powder funnel. Be sure to do this in the hood and wearing your goggles.
If the crystals do not all dissolve, add 2 m L more of the ethanol and continue to warm the mixture to dissolve the crystals. When the crystals are all dissolved, add 10 m L of deionized water, cover the beaker with a watch glass, and allow the solution to cool slowly on the lab bench undisturbed for about 10 minutes. After the 10 minutes cooling on the lab bench, complete the crystallization by placing the beaker and contents in the ice bath. If crystals do not appear, you can scratch the bottom of the beaker with a stirring rod to induce crystallization. Using a clean circle of filter paper, collect the purified aspirin by suction filtration as before. Dry the crystals by pulling air through them for about 15 minutes.
(Discard the filtrate left in the filter flask into the waste container under the hood.
Comments Sythesis Of Aspirin
The Synthesis and Analysis of Aspirin - Semantic Scholar
Periment was to synthesize aspirin by reacting salicylic acid and acetic anhydride in the pres- ence of phosphoric acid to form acetylsalicylic acid. After synthesis.…
Synthesis of Aspirin A General Chemistry Experiment.
It is the two-step synthesis of aspirin starting from oil of wintergreen. The mechanism for this synthesis provides examples of three major classes of chemical.…
Synthesis of Aspirin Experiment - Chemistry LibreTexts
Jun 5, 2019. SYNTHESIS OF ASPIRIN acetylsalicylic acid. Place 2.0 g 0.015 mole of salicylic acid in a 125-mL Erlenmeyer flask. Add 5 mL 0.05 mole of.…
Synthesis of Aspirin Lab - YouTube
Dec 15, 2011. Part of NCSSM CORE collection This video shows the synthesis of aspirin. attribute this work as being created.…
JCE1098 p1261 Synthesis of Aspirin A General Chemistry.
Tial synthesis. It also provides practice in molecular pattern. Synthesis of Aspirin. A General Chemistry Experiment. John Olmsted III. Department of Chemistry.…
Chemistry 104 Synthesis of Aspirin
Chemistry 104 Synthesis of Aspirin. INTRODUCTION Aspirin acetylsalicylic acid is a synthetic organic derived from salicylic acid. Salicylic acid is a natural.…
Synthesis of Aspirin
Aspirin Biological activity. ▫ Analgesic painkiller. ▫ Antipyretic fever reducer. ▫ Anti-inflammatory inhibition of the synthesis of prostaglandins.…
Undergraduate Experiment Synthesis of Aspirin — Benchtop.
Mar 8, 2013. Incorporation of NMR spectroscopy into an undergraduate lab provides an excellent method with which to provide students with practical.…